Morning, long-lifers. Here’s what’s new:

Vitamin D might just be your cellular fountain of youth — it’s not just for your bones anymore, it’s playing bodyguard for your chromosomes.

Turns out your daily dose of sunshine might be better than an anti-aging serum.

Don’t keep longer. a secret—share it with your friends!

This week in longevity:

• 🌲 Forest reset reverses biological aging by 10 years

• 🧠 Stanford’s RNA “mailman” repairs damaged neurons

• 💊 AI finds lifespan-extending drug combos

• 💪 Metformin-galantamine combo reverses muscle loss

• 🧬 New blood test diagnoses rare diseases in days

• Plus, more longevity breakthroughs.

Read time: 5 minutes

THIS WEEK IN LONGEVITY

☀️ Vitamin D shows promise in slowing cell aging

Vitamin D might be more than just a bone booster: a new analysis from the VITAL study suggests daily vitamin D supplements help preserve telomere length (the protective caps on chromosomes), slowing aging by around three years in older adults. Turns out, the sunshine vitamin might also be your cellular sunscreen.

What to know:

• Study details: Researchers tracked 1,054 older adults for four years, checking the health of their chromosomes at multiple points.

• What they found: Vitamin D3 (2,000 IU daily) helped protect these chromosome caps, while omega-3s didn’t.

• Why these caps matter: When they wear down, cells age faster and risks for diseases like heart disease and cancer go up.

• Who might benefit: The trial mostly included older, White adults, so these findings might not apply to everyone equally.

• The bigger picture: More evidence that simple nutrients can make a real difference in how our cells hold up over time.

Not the final word on aging, but it’s a solid reason to keep up with your vitamin D.

Why it’s important: Daily vitamin D supplements could help your cells stay younger for longer — not with expensive treatments, but with a nutrient you can get from the sun or a supplement. Sometimes the simplest tools are the most powerful.

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🌱 Longevity: From ancient quest to luxury status symbol

Forget elixirs of immortality — longevity is the new status flex. From luxury spa treatments to wearable sleep trackers, everyone wants a piece of the anti-aging pie. But while Blue Zones communities live longer thanks to community and fresh air, the luxury crowd is splurging on oxygen therapy and biohacking gadgets.

What to know:

•  It’s everywhere: Longevity is now a buzzword, from five-star hotel menus to high-end skincare brands promising to fight cellular aging.

• The science mix: Some interventions, like diet and social ties, have centuries-old roots; others, like epigenetic testing and blood transfusions, are cutting-edge.

• Competing trends: There’s a split: big money biohacking vs. back-to-basics living. The former is all about technology and measurements; the latter is more about connection and habits.

• Status symbol vibes: Logging perfect sleep scores on your Oura ring is the new brag — luxury wellness now sells the idea of controlling your aging as the ultimate flex.

• What’s next: Experts aren’t sure how long the term longevity will stick around — it might end up as diluted as “wellness,” or pivot into something new.

Live fast, die young? Apparently, we’re over it.

Why it’s important: Longevity’s luxury glow is reshaping how we think about health — it’s become a lifestyle marker, not just a medical goal. The buzz might fade, but the search for better aging won’t. In a world that wants to sell you forever, maybe the best secret is still a walk in the park.

💡 Want to break down a research article? Try this prompt in ChatGPT:
“Explain this in plain language. Avoid science terms. Keep it under 5 sentences. Then give 5 takeaways based only on this summary—no extra info or guesses: [Paste the article here]”

 MONEY MOVES IN LONGEVITY

💰 USC Parris Longevity Accelerator launches with $10M boost — a lifeline for longer, healthier lives.

💰 Juvenescence lands $76M led by M42 — Abu Dhabi’s leap into lifespan-extending drugs.

💰 LSF awards grant to Copenhagen’s Center for Healthy Aging — a fresh shot at reversing brain aging.

💰 Altos Labs acquires Dorian Therapeutics — rejuvenation science turns tactical with fresh talent on board.

 IN THE SPOTLIGHT

1. Midi launches longevity program for women, covered by insurance
Midi Health’s new AgeWell program offers hormone therapy, bloodwork, and longevity care, all backed by insurance — a first in telehealth for women. It’s not just biohacking anymore; real, science-based longevity is finally accessible for women across the U.S.

2. Secrets of superagers unveiled in new review
Long-lived individuals defy aging by blending good genes, stable epigenetics, and balanced metabolism with healthy habits like plant-based diets and regular exercise. Turns out, living past 90 isn’t just luck — it’s a harmonious dance of biology and daily choices.

3. Key protein found to slow skin aging
A new study reveals that p62, a protein helping cells recycle waste, keeps skin firm by reducing harmful inflammation in aging skin cells. Think of it as your skin’s cleanup crew, keeping things fresh and preventing wrinkles from crashing the party.

THE NEXT BIG THING

Doping Olympics?

Getty Images

A new competition will let athletes use performance-enhancing drugs (PEDs) to boost performance.

The Enhanced Games promises $500,000 for each event and requires medical screenings and transparency about what’s being used. Organizers say it’s about reducing the stigma and pushing human limits.

A bold step or just more risk?

WHAT ELSE YOU SHOULD KNOW THIS WEEK

🌲 Forest Reset: Longevity researcher David Furman shaved 10 years off his biological age by living in the forest with his family for 3 years. Trading screens for campfires and fresh fish meals, he reversed inflammation and boosted energy.

🧠 RNA Boost: Stanford researchers developed a CRISPR-based “mailman” that precisely delivers RNA to repair and regrow damaged neurons. In mice neurons, it boosted nerve growth by 50% in just one day!

💊 AI Combo: Machine learning pinpointed drug combos that slow aging by targeting multiple cell pathways at once. In tiny worms, 70% of these combos boosted lifespan to the top 5% ever seen!

💪 Muscle Boost: Rejuvenate Biomed is testing a metformin-galantamine combo that shows promise in reversing age-related muscle loss (sarcopenia). Early studies show it boosts strength and cuts fatigue.

🧬 Fast Breakthrough: A new blood test can diagnose thousands of rare genetic diseases in under three days using just 1 ml of blood. This protein-based method could finally end long, invasive diagnostic odysseys.

WHAT WE’RE BOOKMARKING

📱 Social

🎧 Podcasts

📕Books

⚙️ Tools to Try

Thanks for reading.

See you in the next issue.

Anna

DISCLAIMER: The information provided in this newsletter is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your healthcare provider before making any changes to your health or wellness routine.