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- š¬ The Dolphin Fat That Fights Aging
š¬ The Dolphin Fat That Fights Aging
+ Doing something new rewires your brain

Your weekly longevity insights are here.
Dolphins may hold the key to longer life ā and itās not because theyāre great swimmers.
Turns out, the secret ingredient might be hiding in your cheese drawer, not your supplement cabinet.
Donāt keep longer. a secretāshare it with your friends!
This week in longevity:
š§ One new thing a day sharpens memory
š§« Super stem cells boosted by sugar swap
š§Ŗ Skin cells age in 3 surprising ways
š„ Low-methionine diet reverses frailty in mice
šļø Biohacker slows aging to 8 months per year
Plus, more longevity breakthroughs.
Read time: 5 minutes
THIS WEEK IN LONGEVITY
š¬ Dolphin study sparks discovery of new anti-aging fat

Source: longer. / Midjourney
A rare fat called C15:0, first spotted in US Navy dolphins, may be the newest must-have nutrient for longevity. Scientists found dolphins eating C15:0-rich fish stayed healthier longer, inspiring the creation of a daily supplement called Fatty15. Unlike most wellness trends, this one has solid science behind itāand even better, itās also found in full-fat cheese like pecorino.
What to know:
Discovery by accident: While studying Navy dolphins, researchers found healthier ones had higher levels of C15:0 (a rare saturated fat found in fish and dairy).
How it works: C15:0 helps repair cells, reduce inflammation, improve liver health, and support mitochondria (your cellās energy engines).
Better than Omega-3s?: Surprisingly, C15:0 beat Omega-3s in predicting dolphin health, prompting deeper research into its human benefits.
Hard to get naturally: This fat mostly comes from full-fat dairy and certain fish, but many peopleāespecially vegansādonāt get enough.
Now in supplement form: Fatty15, a vegan capsule version, is backed by 100+ studies and already being used by doctors.
Why itās important: Most supplements donāt live up to the hype, but this one has legit science and a wild backstory involving dolphins. If youāre into aging well, C15:0 might be the real dealāand yes, full-fat cheese could be part of the plan.
MADE POSSIBLE BY VIOME
𧬠Your bodyās not guessing ā so why are your supplements?

Source: Viome
Viomeās Full Body Intelligence Test looks at your microbiome, cellular health, and biological age to show whatās really going on inside.
Then it builds personalized supplements based on your results ā only what your body needs, nothing extra.
Better sleep. Better energy. Better digestion.
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š§ One new thing a day may protect your memory

Source: longer. / Midjourney
Trying one new thing a dayālike a different walking route or talking to someone newācan improve your memory, mood, and even how fast time feels. A University of Toronto study found that āexperiential diversityā (adding new experiences to your routine) helps older adults fight boredom and cognitive decline. But hereās the best part: it benefits people of all ages.
What to know:
Daily novelty matters: Doing something new each dayābig or smallāboosted memory, reduced boredom, and lifted peopleās moods.
Tested during lockdown: Researchers studied 71 seniors during COVID restrictions and saw clear benefits from simple daily changes.
Brain app used: Participants used a tool called HippoCamera (designed to mimic how the brain stores memory) to record and reflect on meaningful moments.
Emotional impact: New experiences helped people feel more present and less isolated, with time feeling like it passed faster.
Anyone can try it: Though focused on older adults, the benefits were seen in all agesāgreat news if youāre feeling stuck in a rut.
Why itās important: You donāt need a gym or a fancy brain gameājust doing one new thing a day can make your brain sharper and your days feel brighter. Itās a simple, feel-good way to fight memory loss and boost mental health, no matter your age.
š” Want to break down a research article? Try this prompt in ChatGPT:
āExplain this in plain language. Avoid science terms. Keep it under 5 sentences. Then give 5 takeaways based only on this summaryāno extra info or guesses: [Paste the article here]ā
MONEY MOVES IN LONGEVITY
š° GSK inks $2.5B deal with ABL Bio to deliver neurodegenerative drugs across the blood-brain barrier using Grabody-B antibody platform.
š° Biolinq raises $100M for a minimally invasive glucose sensor and plans expansion to other metabolic biomarkers for healthspan tracking.
š° Breyer Capital names Morgan Cheatham to lead early-stage healthcare and longevity investments, including AI-driven biomedical tech.
š° Superpower lands $30M to expand its AI-based platform offering biomarker testing, concierge care, and personalized longevity protocols.
IN THE SPOTLIGHT

Source: longer. / Midjourney
1. Your Real Age Might Not Be on Your Birth Certificate
AI apps are changing how we understand aging by tracking ābiological ageāāhow well your body functions, not how long youāve lived. Tools from companies like Rejuve AI, InsideTracker, and Elysium now estimate your health age using DNA and lifestyle data. Experts say this shift could revolutionize how we prevent disease and stay healthy longer.
2. New NAD Booster Enters Human Trials to Target Aging at the Source
MetroBiotech just dosed the first volunteers in a trial for MIB-725, a new compound designed to boost NAD+ (a molecule vital for energy and cell repair) through a unique pathway. MIB stands for āMetroBiotech Investigational Booster,ā and this version may work better than NMN. Early results show no serious side effects, marking a hopeful step in treating age-related disease.
3. Stronger Immunity in Midlife Could Help You Age Better
New research shows that people with strong immune resilienceāyour bodyās ability to fight diseaseālive longer and healthier lives. Those aged 40ā70 with high immune resilience had a 69% lower risk of death, thanks to better protection against inflammation and aging. Boosting this defense early may be key to avoiding chronic illness later in life.
NEXT-GEN LONGEVITY
THE NEXT BIG THING
Is Sweat the Next Health Tracker?

Source: Epicore Biosystems
A new patch reads your sweatāno needles, no blood.
Epicoreās patch monitors hydration, salt levels, and temperature in real time. Now itās being tested for kidney function, stress, and vitamin levelsāusing the sweat your body produces all day, even without exercise.
A new layer of insight from something we usually wipe away.
QUICK HITS
WHAT ELSE YOU SHOULD KNOW THIS WEEK

Source: longer. / Midjourney
š§Ŗ Aging Paths: Johns Hopkins researchers found skin cells age in three distinct ways, not just one. Each path responds differently to anti-aging drugs, opening doors to precision longevity therapies.
š„ Protein Shift: Cutting methionine (a protein-building amino acid) in older mice improved muscle strength, brain function, and reduced frailty. The benefits kicked in fastāeven when the diet began late in life.
š ļø Aging Tools: Biohacker Bryan Johnson, 47, swears by stainless steel meals, red light therapy, and wearable trackers to slow his aging to 8 months per year. His toolsāfrom olive oil to a smart bedāaim to boost daily longevity.
𧬠Protein Power: Bar-Ilan scientists found long-lived mammals like whales share key protein changes that guard against aging and disease. These tweaks in acetylation (a chemical tag) could unlock therapies for longer, healthier lives.
š§« Super Cells: University of Copenhagen scientists created āsuper stem cellsā by switching their energy source from glucose to galactose. The tweak boosted cell performance and could improve IVF success and regenerative therapies.
WHAT WEāRE BOOKMARKING
š± Social
Your first 10 minutes after waking set your biology in motion.
Sunlight = Cortisol aligned
Grounding = Inflammation lowered
Breathwork = Nervous system resetSkip the scroll. GET OUTSIDE
ā Gary Brecka (@thegarybrecka)
11:04 AM ⢠Apr 30, 2025
Much stress is not due to what happens to us but rather how we react to what happens to us.
How do you react?
ā Robert Lufkin MD (@robertlufkinmd)
8:56 PM ⢠Apr 29, 2025
š§ Podcasts
š° Articles
Chemical additives in plastics (phthalates) and cardiovascular mortality
thelancet.com/journals/ebiomā¦ā Eric Topol (@EricTopol)
1:36 PM ⢠Apr 29, 2025
āļø Tools to Try
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