Welcome,

Your weekly longevity insights are here.

The FDA just approved a credit card-sized heart monitor—finally, a gadget your wallet can’t complain about carrying.

Let’s hope your heart behaves better than your spending habits.

Don’t keep longer. a secret—share it with your friends!

This week in longevity:

• 🧠 AI predicts brain age from lifestyle habits

• 💊 Green tea compound slows heart aging

• 🫀 MRI identifies risky heart fat early

• 🤖 AI outperforms doctors in skin cancer detection

• 🏆 XPRIZE races to reverse aging in one year

• Plus, more longevity breakthroughs.

Read time: 5 minutes

THIS WEEK IN LONGEVITY

FEATURED

💳 FDA clears credit card-sized heart monitor

HeartBeam, a California healthcare company, has received FDA clearance for its innovative heart monitor—a device the size of a credit card that creates full 12-lead electrocardiograms (ECGs). It’s designed to let people check their heart health in real-time, from anywhere.

What to know:

• What it does: The device records a 30-second ECG by guiding users through placement via an app. The data is sent to the cloud for review by a doctor.

• Why it matters: Many patients delay getting help for heart symptoms, worsening their outcomes. This device lets them act fast.

• Future potential: HeartBeam plans to enhance the device with AI-powered risk detection for heart attacks and other cardiac issues.

• Real-world testing: A study with nearly 200 patients is underway to confirm its effectiveness in real-life scenarios.

• Global impact: The company sees this as a game-changer for managing heart health anywhere in the world.

Why it’s important: Heart disease is a leading cause of death, and fast diagnosis saves lives. This pocket-sized monitor could empower patients to catch warning signs early, giving them a lifeline when every second counts.

FEATURED

🧬 5 science-backed habits to live longer

Longevity scientist Dr. Joseph Antoun, with 20+ years of experience, says living longer isn’t about shortcuts. It’s about consistent habits that boost cellular health. He highlights five key pillars to focus on: nutrition, physical activity, sleep, stress management, and social connections.

What to know:

• Nutrition is key:

• Try time-restricted eating (12–14 hours of overnight fasting) to kickstart autophagy (cell cleanup).

• Eat 30+ types of plants weekly for a diverse, nutrient-rich diet.

• Consider a Fasting Mimicking Diet (FMD), like Prolon, a few times a year to renew cells and support metabolism.

• Get moving: Regular physical activity strengthens your heart, muscles, and brain, keeping you healthier as you age.

• Prioritize sleep: Quality rest repairs your body and mind. Aim for 7–9 hours nightly.

• Tame stress: Chronic stress speeds up aging. Try meditation, exercise, or hobbies to unwind.

• Build strong connections: Close friendships and family bonds improve mental health and even extend lifespan.

Why it’s important: Small, consistent changes can add years to your life and make those years healthier. Start with one pillar—like improving your diet—and build from there. Your future self will thank you!

💡Pro Tip: Want to dive deeper? Use tools like ChatGPT, Claude, or Gemini to simplify complex studies. Copy, paste, and get a clear summary—it’s like having a personal research assistant.

IN THE SPOTLIGHT

1. Healthy Lifestyles Linked to Younger-Looking Brains
Researchers at Karolinska Institutet used AI to estimate the biological age of 70-year-old brains, finding that healthy habits like regular exercise were tied to younger-looking brains. Meanwhile, factors like high blood sugar and inflammation were linked to older brain appearances. The study highlights how keeping blood vessels healthy can protect brain aging, offering insights into resilience against conditions like dementia and Alzheimer’s disease.

2. New MRI Method Could Predict Heart Disease Risk by Analyzing Heart Fat
Scientists at the University of Virginia have developed an MRI technique to measure the type and amount of fat surrounding the heart, known as epicardial adipose tissue. This fat can release harmful substances into the heart, raising the risk of conditions like coronary artery disease and heart failure. By identifying unhealthy fat composition early, doctors could personalize treatments, including diet, exercise, or medication, to reduce heart disease complications.

3. Green Tea Compound May Prevent Aging-Related Heart Problems
A study published in Genes & Diseases reveals that EGCG, a powerful antioxidant found in green tea, can help prevent heart dysfunction related to aging. Research in older mice showed that EGCG reduced heart tissue damage, improved heart function, and increased levels of cardiac troponin I, a protein essential for heart health. This highlights the potential of green tea compounds as a natural way to protect the heart as we age.

LONGEVITY SNAPSHOTS

WHAT ELSE YOU SHOULD KNOW THIS WEEK

🤖 AI Breakthrough: Researchers developed an AI model with 94.49% accuracy to detect skin cancer early, surpassing current diagnostic tools. This model uses advanced techniques like transfer learning and test time augmentation, promising faster, life-saving diagnoses worldwide.

🧬 Reproductive Genetics: Oxford and Icelandic researchers uncovered 37 genes linking reproductive health, longevity, and overall well-being. Key findings reveal genes like FSHB (regulates reproductive hormones) affect fertility, menopause, and hormone-sensitive cancer risks, reshaping personalized healthcare.

💊 Pain Relief: The FDA cleared Sangamo's ST-503 for trials targeting chronic neuropathic pain caused by iSFN (idiopathic small fiber neuropathy). This therapy uses zinc finger proteins (customized DNA-binding molecules) to silence pain-signaling genes, offering hope for untreatable pain sufferers.

🧠 Neurotech Milestone: Precision Neuroscience raised $102M to advance its AI-powered brain implant for operating devices via thought alone. Its innovative Layer 7 Cortical Interface (flexible brain electrode) promises safer, minimally invasive solutions for paralysis and neurological disorders.

🏆 Aging Revolution: The $101M XPRIZE Healthspan competition aims to reverse aging markers by 10-20 years in under one year. With 554 global teams competing, solutions combine lifestyle interventions with cutting-edge therapies like gene editing and stem cells.

PROMPT OF THE DAY

Stress Reset

WHAT WE’RE BOOKMARKING

📱 Social

🎧 Podcasts

• Well with Arielle Lorre: "How to Use Sound to Heal Your Body, Enhance Your Life & Make Your Manifestations Come True": Explore how sound frequencies can transform your health and amplify your manifestations. (Apple link).

• The Skinny Confidential: "JJ Virgin On Mindful Eating, Body Composition, & Powerful Aging Strategies That Work": Discover how mindful eating, body composition, and transformative health strategies can help you age powerfully. (Spotify link).

📚 Books

• "Life Force" by Tony Robbins: Learn how precision medicine and regenerative technologies can enhance your health and extend your lifespan. (Amazon link).

⚙️ Tools to Try

• Living to 100 Life Expectancy Calculator: Discover how lifestyle choices impact your longevity with this personalized life expectancy tool. (Product website).

Thanks for reading.

See you in the next issue.

Anna

DISCLAIMER: The information provided in this newsletter is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your healthcare provider before making any changes to your health or wellness routine.